Sneddon syndrome: a rare non-inflammatory thrombotic vasculopathy

Abstract

Sneddon syndrome is a rare disease that mostly affects women. It is a non-inflammatory thrombotic vasculopathy associated with cerebro-vascular events and livedo reticularis. The most affected districts in fact involve the medium and small caliber arteries borne by the brain and the skin. The etiology is unknown but it is believed that the levels of female reproductive hormones, the use of oral contraceptives and systemic arterial hypertension may be correlated with the progression of the disease.
We report the case of a 50-year-old woman who had a previous cerebral stroke, systemic arterial hypertension, livedo reticularis and changes in the immune and coagulation system in the medical history.